Eric Dane, the American actor best known for his role as Dr Mark Sloan in Grey’s Anatomy, has died at the age of 53 after living with amyotrophic lateral sclerosis (ALS), also known as Charcot’s disease.
For many fans, Dane will always be remembered as “McSteamy,” the confident and charismatic plastic surgeon who became one of the defining characters of the long-running medical drama. He joined Grey’s Anatomy in 2006 and quickly became a central figure in the series, remaining a fan favourite for more than a decade before his departure in 2021.
In recent years, Dane took on new challenges, appearing in HBO’s Euphoria, where he delivered a raw and emotionally complex performance that showcased a different side of his talent. In April 2025, he publicly revealed that he had been diagnosed with ALS, a progressive neurological disease that affects muscle control. Despite the diagnosis, he continued to be admired for his openness and courage.
Dane also had a connection to Monaco. In 2007, at the height of his Grey’s Anatomy fame, he attended the Monte-Carlo Television Festival, walking the red carpet in the Principality and meeting His Serene Highness Prince Albert II during the event.
News of his passing has prompted an outpouring of tributes from colleagues and fans around the world, many remembering not only his screen presence but also his warmth and generosity. His portrayal of Dr Sloan left a lasting mark on television — and on the millions who followed his story.